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Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen shares 95% identity with rat.
Specificity of this antibody: CHMP6.
CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Charged multivesicular body protein 6; chromatin modifying protein 6; Chromatin-modifying protein 6; novel SNF7 protein
基因别名: 2400004G01Rik; Chmp6; RGD1565325
UniProt ID: (Mouse) P0C0A3
Entrez Gene ID: (Mouse) 208092, (Rat) 287873