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Immunogen sequence: QFGNECLNKM HQVMSIEEVE RILDETQEAV EYQRQIDELL AGSFTQEDED AILEELSAIT QEQIELPEVP SEPLPEKIPE NVPVK
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 88%.
CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Charged multivesicular body protein 6; chromatin modifying protein 6; Chromatin-modifying protein 6; hVps20; Vacuolar protein sorting-associated protein 20; Vps20
基因别名: CHMP6; VPS20
UniProt ID: (Human) Q96FZ7
Entrez Gene ID: (Human) 79643