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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
In direct ELISAs and Western blots, no cross-reactivity with recombinant human CHRDL2, recombinant mouse (rm) CHRDL1, or rmChordin is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
CHRDL2 encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: chordin like 2; Chordin-like protein 2; FKSG37
基因别名: 1810022C01Rik; Chl2; Chrdl2
UniProt ID: (Mouse) Q8VEA6
Entrez Gene ID: (Mouse) 69121