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Positive test controls include: B cells, HeLa, HT-1080, Jurkat, Mouse thymus, Rat brain, Rat thymus. The target is usually found in the following locations: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse.
Immunogen sequence: ADGKYAQKLF NDLFEDYSNA LRPVEDTDKV LNVTLQITLS QIKDMDERNQ ILTAYLWIRQ IWHDAYLTWD RDQYDGLDSI RIPSDLVWRP DIVLYNKADD ESSEPVNTNV VLRYDGLITW DAPAITKSSC VVDVTYFPFD NQQCNLTFGS WTYNGNQVDI FNALDSGDLS DFIEDVEWEV HGMPAVKNVI SYGCCSEPYP DVTFTLLLKR RSSFY
CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 is a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acetylcholine receptor; acetylcholine receptor alpha 9 subunit (nAChR); acetylcholine receptor, neuronal nicotinic, alpha-9 subunit; cholinergic receptor; cholinergic receptor, nicotinic alpha 9; cholinergic receptor, nicotinic, alpha 9 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 9; NACHR alpha 9; NACHR alpha-9; neuronal acetylcholine receptor protein, alpha-9 subunit; Neuronal acetylcholine receptor subunit alpha-9; nicotinic acetylcholine receptor subunit alpha 9; Nicotinic acetylcholine receptor subunit alpha-9
基因别名: 2410015I05Rik; Acra9; CHRNA9; EG666827; Gm8311; HSA243342; NACHRA9
UniProt ID: (Human) Q9UGM1, (Rat) P43144
Entrez Gene ID: (Human) 55584, (Mouse) 231252, (Rat) 65024
分子生物学功能: ligand-gated ion channel