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Invitrogen
CHRNB3 Polyclonal Antibody
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CHRNB3 Antibody (PA5-103970) in IHC (P)
Immunohistochemistry analysis of CHRNB3 in rat heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with CHRNB3 polyclonal antibody (Product # PA5-103970) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103970
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CHRNB3(Accession Q05901), corresponding to amino acid residues L185-F235.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CHRNB3.
靶标信息
The nicotinic acetylcholine receptors are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor, neuronal nicotinic, beta-3 subunit; acetylcholine receptor, nicotinic, beta 3 (neuronal); cholinergic receptor; cholinergic receptor, nicotinic beta 3; cholinergic receptor, nicotinic, beta 3 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 3; neuronal nicotinic; neurotransmitter receptor; unnamed protein product
基因别名: 5730417K16Rik; Acrb3
UniProt ID: (Human) Q05901, (Rat) P12391, (Mouse) Q8BMN3
Entrez Gene ID: (Human) 1142, (Rat) 171131, (Mouse) 108043
ion transport
calcium ion transport
synaptic transmission, cholinergic
neuromuscular synaptic transmission
ion transmembrane transport
response to nicotine
membrane depolarization
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
acetylcholine receptor signaling pathway
presynaptic modulation of chemical synaptic transmission
chemical synaptic transmission, postsynaptic
modulation of synaptic transmission
cell communication
signal transduction
signaling
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