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Invitrogen
CHRNE Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-76134
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein of human CHRNE.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor epsilon; acetylcholine receptor, nicotinic, epsilon (muscle); AchR epsilon subunit; ACHRG; cholinergic receptor; cholinergic receptor, nicotinic epsilon; cholinergic receptor, nicotinic, epsilon (muscle); cholinergic receptor, nicotinic, epsilon polypeptide; epsilon-subunit; gene for acetylcholine receptor epsilon subunit; MGC133376; myasthenia gravis, familial infantile, 1; nicotinic acetylcholine receptor epsilon subunit; unnamed protein product
基因别名: ACHRE; AChrepsilon; Acre; CMS1A1; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; FIM1; FIMG; FIMG1; MGI; nAChR; nAChRE; SCCMS
UniProt ID: (Human) Q04844, (Rat) P09660, (Mouse) P20782
Entrez Gene ID: (Human) 1145, (Rat) 29422, (Mouse) 11448
transmembrane signaling receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
cation transmembrane transporter activity
acetylcholine receptor activity
acetylcholine-gated cation channel activity
postsynaptic neurotransmitter receptor activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
skeletal muscle contraction
ion transport
calcium ion transport
muscle contraction
signal transduction
synaptic transmission, cholinergic
ion transmembrane transport
regulation of membrane potential
membrane depolarization
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
acetylcholine receptor signaling pathway
cation transmembrane transport
chemical synaptic transmission, postsynaptic
cation transport
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