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Invitrogen
CHRNE Polyclonal Antibody
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CHRNE Antibody (PA5-87600) in WB
Western blot analysis of CHRNE in extracts of various cell lines. Samples were incubated with CHRNE Polyclonal antibody (Product # PA5-87600) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-87600
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CHRNE (NP_0000711)
偶联物
形式
Liquid
浓度
1.28 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: KNEELRLYHH LFNNYDPGSR PVREPEDTVT ISLKVTLTNL ISLNEKEETL TTSVWIGIDW QDYRLNYSKD DFGGIETLRV PSELVWLPEI VLENNIDGQF GVAYDANVLV YEGGSVTWLP PAIYRSVCAV EVTYFPFDWQ NCSLIFRSQT YNAEEVEFTF AVDNDGKTIN KIDIDTEAYT ENGEWAIDFC PGVIRRHHGG ATDGPGETDV IYSLIIRRK; Positive Samples: HepG2, Mouse skeletal muscle, Rat kidney, Rat skeletal muscle; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
靶标信息
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor epsilon; Acetylcholine receptor subunit epsilon; acetylcholine receptor, nicotinic, epsilon (muscle); AchR epsilon subunit; ACHRG; cholinergic receptor; cholinergic receptor, nicotinic epsilon; cholinergic receptor, nicotinic, epsilon (muscle); cholinergic receptor, nicotinic, epsilon polypeptide; epsilon-subunit; gene for acetylcholine receptor epsilon subunit; MGC133376; nicotinic acetylcholine receptor epsilon subunit
基因别名: ACHRE; AChrepsilon; Acre; CHRNE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; nAChRE; SCCMS
UniProt ID: (Human) Q04844, (Mouse) P20782, (Rat) P09660
Entrez Gene ID: (Human) 1145, (Mouse) 11448, (Rat) 29422
