Search Thermo Fisher Scientific
图: 1 / 6
CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A18 hnRNP; cold inducible RNA-binding protein; Cold-inducible RNA-binding protein; glycine-rich RNA binding protein; Glycine-rich RNA-binding protein CIRP; testicular tissue protein Li 39
基因别名: A18HNRNP; CIRBP; CIRP
UniProt ID: (Human) Q14011
Entrez Gene ID: (Human) 1153