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Invitrogen
CK1 delta Monoclonal Antibody (C3)
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CK1 delta Antibody (MA5-50957) in IHC (P)
Immunohistochemistry (Paraffin) analysis of CK1 delta in human cerebrum tissue using CK1 delta Monoclonal Antibody (C3) (Product # MA5-50957) (30 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Mouse IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
产品信息
MA5-50957
产品规格
种属反应
Human,
Pig,
Rat
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
C3
抗原
Recombinant Human CSNK1d protein, Met1-Lys409 (Accession #P48730)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% Proclin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for CK1 delta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: casein kinase 1; casein kinase 1, delta; casein kinase 1, delta tv1; casein kinase 1, delta tv2; Casein kinase I isoform delta; CK1d; CK1delta; CKI-delta; CKId; HGNC:2452; Tau-protein kinase CSNK1D
基因别名: ASPS; CKIdelta; CSNK1D; FASPS2; HCKID
UniProt ID: (Human) P48730, (Rat) Q06486
Entrez Gene ID: (Pig) 100625051, (Human) 1453, (Rat) 64462
G2/M transition of mitotic cell cycle
positive regulation of protein phosphorylation
DNA repair
rRNA processing
protein phosphorylation
endocytosis
microtubule nucleation
Golgi organization
signal transduction
regulation of cell shape
Wnt signaling pathway
peptidyl-serine phosphorylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
circadian regulation of gene expression
protein localization to Golgi apparatus
nonmotile primary cilium assembly
regulation of circadian rhythm
COPII vesicle coating
spindle assembly
protein localization to cilium
protein localization to centrosome
positive regulation of canonical Wnt signaling pathway
cell-cell adhesion
cellular response to nerve growth factor stimulus
positive regulation of non-canonical Wnt signaling pathway
mitotic cell cycle
