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Invitrogen
CK1 gamma-3 Polyclonal Antibody
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CK1 gamma-3 Antibody (PA5-88914) in WB
Western blot analysis of CK1 gamma-3 in extracts of various cell lines. Samples were incubated with CK1 gamma-3 Polyclonal antibody (Product # PA5-88914) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88914
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 304-423 of human CSNK1G3 (NP_0010269821)
偶联物
形式
Liquid
浓度
0.68 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LRKLFTDLFD RKGYMFDYEY DWIGKQLPTP VGAVQQDPAL SSNREAHQHR DKMQQSKNQV VSSTNGELNT DDPTAGRSNA PITAPTEVEV MDETNCQKVL NMWCCCFFKR RKRKTIQRHK; Positive Samples: Mouse eye, Mouse brain, Rat heart; Cellular Location: Cytoplasm
靶标信息
The casein kinase I (CKI) gene family encodes serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric and range from 25 to 55 kD. They are ubiquitous, being found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells. In eukaryotic cells, CKI is in volved in regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Casein kinase I isoform gamma-3; CKI-gamma 3
基因别名: 3300002K07Rik; C330049O21Rik; Csnk1g3
UniProt ID: (Mouse) Q8C4X2, (Rat) Q62763
Entrez Gene ID: (Mouse) 70425, (Rat) 64823
nucleotide binding
magnesium ion binding
glycoprotein binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
peptide binding
phosphoprotein binding
non-receptor serine/threonine protein kinase
