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Invitrogen
CKAP2 Polyclonal Antibody
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CKAP2 Antibody (PA5-35867) in ICC/IF
CKAP2 Polyclonal Antibody detects CKAP2 protein at cytoskeleton by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: CKAP2 protein stained by CKAP2 Polyclonal Antibody (Product # PA5-35867) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-35867
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CKAP2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Recommended positive controls: Raji, NCI-H929.
Predicted reactivity: Mouse (82%), Rat (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CKAP2; CTCL tumor antigen se20-10; Cytoskeleton-associated protein 2; Tumor- and microtubule-associated protein; tumor-associated microtubule-associated protein
基因别名: CKAP2; LB1; se20-10; TMAP
UniProt ID: (Human) Q8WWK9
Entrez Gene ID: (Human) 26586
