Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
CKAP4 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
PA5-96803
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
2.8 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: 293T, HepG2, MCF7, NCI-H460, Mouse testis; Cellular Location: Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Single-pass type II membrane protein, cytoskeleton, perinuclear region
Immunogen sequence: VLEEVQQVRR SHQDFSRQRE ELGQGLQGVE QKVQSLQATF GTFESILRSS QHKQDLTEKA VKQGESEVSR ISEVLQKLQN EILKDLSDGI HVVKDARERD FTSLENTVEE RLTELTKSIN DNIAIFTEVQ KRSQKEINDM KAKVASLEES EGNKQDLKAL KEAVKEIQTS AKSREWDMEA LRSTLQTMES DIYTEVRELV SLKQEQQAFK EAADTERLAL QALTEKLLRS EESVSRLPEE IRRLEEELRQ LKSDSHGPKE DGGFRHSEAF E
靶标信息
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14. 7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 63 kDa membrane protein; 63-kDa cytoskeleton-linking membrane protein; Climp-63; Cytoskeleton-associated protein 4; transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment; type-II transmembrane protein p63
基因别名: 5630400A09Rik; CKAP4; CLIMP-63; ERGIC-63; P63
UniProt ID: (Human) Q07065, (Mouse) Q8BMK4
Entrez Gene ID: (Human) 10970, (Mouse) 216197, (Rat) 362859
