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Proteintech
RACGAP1 Monoclonal Antibody (6E10A2), CoraLite® Plus 488
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Product Details
CL488-66056
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6E10A2
Immunogen
Fusion Protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AKT; CYK4; GAP; ID; Male germ cell RacGap; MGC99656; MgcRacGAP; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase-activating protein 1; RAC-ALPHA; RACGAP1; unnamed protein product
Gene Aliases: AI227039; AI327394; Band25; CDAN3B; CYK4; gtl11; GTPase; HsCYK-4; ID-GAP; KIAA1478; MGCRACGAP; mKIAA1478; RACGAP1; RCGAP1
UniProt ID: (Human) Q9H0H5, (Mouse) Q9WVM1
Entrez Gene ID: (Human) 29127, (Mouse) 26934, (Rat) 315298
mitotic cytokinesis
actomyosin contractile ring assembly
ion transport
signal transduction
Rho protein signal transduction
spermatogenesis
neuroblast proliferation
cell differentiation
erythrocyte differentiation
positive regulation of cytokinesis
regulation of embryonic development
regulation of small GTPase mediated signal transduction
mitotic spindle midzone assembly
cell division
regulation of attachment of spindle microtubules to kinetochore
sulfate transmembrane transport
transport
cell cycle
multicellular organism development
sulfate transport
embryo development
intracellular signal transduction
positive regulation of GTPase activity
mitotic spindle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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