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Proteintech
Neuroserpin Monoclonal Antibody (1G4C6), CoraLite® Plus 488
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产品信息
CL488-66997
产品规格
种属反应
Human,
Pig,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1G4C6
抗原
Neuroserpin fusion protein Ag28636
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: ANSLFVQNG FHVNEEFLQM MKKYFNAAVN HVDFSQNVAV ANYINKWVEN NTNNLVKDLV SPRDFDAATY LALINAVYFK GNWKSQFRPE NTRTFSFTKD DESEVQIPMM YQQGEFYYGE FSDGSNEAGG IYQVLEIPYE GDEISMMLVL SRQEVPLATL EPLVKAQLVE EWANSVKKQK VEVYLPRFTV EQEIDLKDVL KALGITEIFI KDANLTGLYD NKEIFLSKAI HKSFLEVNEE GSEAAAVSGM IAISRMAVLY PQVIVDHPFF FLIRNRRTGT ILFMGRVMHP ETMNTSGHDF EEL
靶标信息
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp781N13156; Neuroserpin; Peptidase inhibitor 12; PI-12; protease inhibitor 17; serine (or cysteine) peptidase inhibitor, clade I, member 1; serine (or cysteine) proteinase inhibitor clade member 1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; Serine protease inhibitor 17; Serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; serpin peptidase inhibitor, clade I, member 1
基因别名: neuroserpin; PI-12; PI12; raPIT5a; SERPINI1; Spi17
UniProt ID: (Human) Q99574, (Rat) Q9JLD2
Entrez Gene ID: (Pig) 100154352, (Human) 5274, (Rat) 116459
