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Proteintech
IDE Monoclonal Antibody (3E10G1), CoraLite® Plus 488
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产品信息
CL488-67106
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
3E10G1
抗原
Recombinant protein
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: EQPHQHAMYY LRLLMTEVAW TKDELKEALD DVTLPRLKAF IPQLLSRLHI EALLHGNITK QAALGIMQMV EDTLIEHAHT KPLLPSQLVR YREVQLPDRG WFVYQQRNEV HNNCGIEIYY QTDMQSTSEN MFLELFCQII SEPCFNTLRT KEQLGYIVFS GPRRANGIQG LRFIIQSEKP PHYLESRVEA FLITMEKSIE DMTEEAFQKH IQALAIRRLD KPKKLSAECA KYWGEIISQQ YNFDRDNTEV AYLKTLTKED IIKFYKEMLA VDAPRRHKVS VHVLAREMDS CPVVGEFPCQ NDINLSQAPA LPQPEVIQNM TEFKRGLPLF PLVKPHINFM AAKL
靶标信息
This gene may belong to a protease family responsible for intercellular peptide signalling. Though its role in the cellular processing of insulin has not yet been defined, insulin-degrading enzyme is thought to be involved in the termination of the insulin response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Abeta-degrading protease; FLJ35968; Insulin degrading enzyme; Insulin protease; Insulin-degrading enzyme; Insulinase; Insulysin
基因别名: 1300012G03Rik; 4833415K22Rik; AA675336; AI507533; IDE; INSDEGM; INSULYSIN
UniProt ID: (Human) P14735, (Rat) P35559
Entrez Gene ID: (Human) 3416, (Rat) 25700, (Mouse) 15925
beta-amyloid binding
virus receptor activity
glycoprotein binding
metalloendopeptidase activity
receptor binding
protein binding
ATP binding
zinc ion binding
ATPase activity
beta-endorphin binding
peptide binding
protein homodimerization activity
ubiquitin binding
insulin binding
peptidase activity
peptide hormone binding
nucleotide binding
catalytic activity
metallopeptidase activity
hydrolase activity
metal ion binding
metalloprotease
proteolysis
insulin receptor signaling pathway
determination of adult lifespan
bradykinin catabolic process
ubiquitin homeostasis
protein processing
positive regulation of protein oligomerization
hormone catabolic process
negative regulation of proteolysis
viral entry into host cell
beta-amyloid metabolic process
protein homooligomerization
protein homotetramerization
protein heterooligomerization
proteolysis involved in cellular protein catabolic process
insulin metabolic process
insulin catabolic process
peptide catabolic process
cellular protein catabolic process
metabolic process
