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Proteintech
SHMT1 Monoclonal Antibody (2D5E6), CoraLite® Plus 488
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产品信息
CL488-67963
产品规格
种属反应
Human,
Pig,
Rabbit
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2D5E6
抗原
SHMT1 fusion protein Ag5833
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: PHGRIMGLD LPDGGHLTHG FMTDKKKISA TSIFFESMPY KVNPDTGYIN YDQLEENARL FHPKLIIAGT SCYSRNLEYA RLRKIADENG AYLMADMAHI SGLVAAGVVP SPFEHCHVVT TTTHKTLRGC RAGMIFYRKG VKSVDPKTGK EILYNLESLI NSAVFPGLQG GPHNHAIAGV AVALKQAMTL EFKVYQHQVV ANCRALSEAL TELGYKIVTG GSDNHLILVD LRSKGTDGGR AEKVLEACSI ACNKNTCPGD RSALRPSGLR LGTPALTSRG LLEKDFQKVA HFIHRGIELT LQIQSDTGVR ATLKEFKERL AGDKYQAAVQ ALREEVESFA SLFPLPGLPD F
靶标信息
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytoplasmic serine hydroxymethyltransferase; cytosolic serine hydroxymethyltransferase; Glycine hydroxymethyltransferase; MGC15229; MGC24556; serine hydroxymethyltransferase 1 (soluble); serine hydroxymethyltransferase 2 (mitochondrial); Serine hydroxymethyltransferase, cytosolic; Serine methylase; SHMT
基因别名: CSHMT; MEL-32; SHMT; SHMT1
UniProt ID: (Human) P34896, (Rabbit) P07511
Entrez Gene ID: (Pig) 397181, (Human) 6470, (Rabbit) 100009405
dTMP biosynthetic process
glycine metabolic process
L-serine metabolic process
L-serine catabolic process
purine nucleobase biosynthetic process
glycine biosynthetic process from serine
tetrahydrofolate interconversion
carnitine biosynthetic process
tetrahydrofolate metabolic process
folic acid metabolic process
protein tetramerization
protein homotetramerization
cellular response to tetrahydrofolate
