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Proteintech
MAN1B1 Monoclonal Antibody (3C9F10), CoraLite® Plus 488
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产品信息
CL488-68121
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
3C9F10
抗原
MAN1B1 fusion protein Ag28302
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: LFLRKAEDF GNRLMPAFRT PSKIPYSDVN IGTGVAHPPR WTSDSTVAEV TSIQLEFREL SRLTGDKKFQ EAVEKVTQHI HGLSGKKDGL VPMFINTHSG LFTHLGVFTL GARADSYYEY LLKQWIQGGK QETQLLEDYV EAIEGVRTHL LRHSEPSKLT FVGELAHGRF SAKMDHLVCF LPGTLALGVY HGLPASHMEL AQELMETCYQ MNRQMETGLS PEIVHFNLYP QPGRRDVEVK PADRHNLLRP ETVESLFYLY RVTGDRKYQD WGWEILQSFS RFTRVPSGGY SSINNVQDPQ KPEPRDKMES FFLGETLKYL FLLFSDDPNL LSLDAYVFNT EAHPLPIWTP A
靶标信息
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2. Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544]. Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699]. Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3.2.1.113; endoplasmic Reticulum Class I alpha-mannosidase; Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1; ER alpha 1,2-mannosidase; ER alpha-1,2-mannosidase; ER mannosidase 1; ERMan1; Man9GlcNAc2-specific processing alpha-mannosidase; Man9GlcNAc2-specific-processing alpha-mannosidase; Mannosidase alpha class 1B member 1; mannosidase, alpha, class 1B, member 1; RP11-350O14.2
基因别名: ERMAN1; ERManI; MAN1B1; MANA-ER; MRT15; UNQ747/PRO1477
UniProt ID: (Human) Q9UKM7
Entrez Gene ID: (Human) 11253
