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Proteintech
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Immunogen sequence: FTVHMAARII AKLAAWGKEL MEGSDLNYYF NWIKTQLSSQ KLRGSGVAVE TGTVSSSDSS QYVQCVAGCL QLMLRVNEYR FAWVEADGVN CIMGVLSNKC GFQLQYQMIF SIWLLAFSPQ MCEHLRRYNI IPVLSDILQE SVKEKVTRII LAAFRNFLEK STERETRQEY ALAMIQCKVL KQLENLEQQK YDDEDISEDI KFLLEKLGES VQDLSSFDEY SSELKSGRLE WSPVHKSEKF WRENAVRLNE KNYELLKILT KLLEVSDDPQ VLAVAAHDVG EYVRHYPRGK RVIEQLGGKQ LVMNHMHHED QQVRYNALLA VQKLMVHNWE YLGKQLQSEQ PQTAAARS
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 54 kDa vacuolar H(+)-ATPase subunit; ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H; NBP1; Nef-binding protein 1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; V-ATPase H subunit; V-ATPase subunit H; V-type proton ATPase subunit H; vacuolar ATP synthase subunit H; vacuolar ATPase subunit H; vacuolar proton pump H subunit; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD
基因别名: 0710001F19Rik; ATP6V1H; AU022349; CGI-11; MSTP042; NBP1; SFD; SFDalpha; SFDbeta; V-ATPASE; VMA13
UniProt ID: (Human) Q9UI12, (Pig) Q9TVC1, (Mouse) Q8BVE3
Entrez Gene ID: (Human) 51606, (Pig) 397472, (Rabbit) 100353410, (Mouse) 108664, (Rat) 297797