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Proteintech
Nucleolin/C23 Recombinant Rabbit Monoclonal Antibody (240029F8), CoraLite® Plus 488
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Product Details
CL488-83380
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
240029F8
Immunogen
Nucleolin/C23 fusion protein Ag0859
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MVKLAKAGKN QGDPKKMAPP PKEVEEDSED EEMSEDEEDD SSGEEVVIPQ KKGKKAAATS AKKVVVSPTK KVAVATPAKK AAVTPGKKAA ATPAKKTVTP AKAVTTPGKK GATPGKALVA TPGKKGAAIP AKGAKNGKNA KKEDSDEEED DDSEEDEEDD EDEDEDEDEI EPAAMKAAAA APASEDEDDE DDEDDEDGKS KGIAYIEFKT EADAEKTFEE KQGTEIDGRS ISLYYTGEKG QNQDYRGGKN STWSGESKTL VLSNLSYSAT EETLQEVFEK ATFIKVPQNQ NGKSKGYAFI EFASFEDAKE ALNSCNKREI EGRAIRLELQ GPRGSPNARS QPSKTLFVKG LSEDTTEETL KESFDGSVRA RIVTDRETGS SKGFGFVDFN SEEDAKAAKE AMEDGEIDGN KVTLDWAKPK GEGGFGGRGG GRGGFGGRGG GRGGRGGFGG RGRGGFGGRG GFRGGRGGGG DHKPQGKKTK FE
Target Information
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ45706; FLJ59041; nucl antibody; Nucleolin; Protein C23
Gene Aliases: C23; NCL
UniProt ID: (Human) P19338
Entrez Gene ID: (Human) 4691
nucleotide binding
single-stranded DNA binding
RNA binding
calcium ion binding
protein binding
protein C-terminus binding
selenocysteine insertion sequence binding
rRNA primary transcript binding
telomeric DNA binding
histone binding
identical protein binding
laminin binding
poly(A) RNA binding
ErbB-4 class receptor binding
angiogenesis
endocytosis
spermatogenesis
positive regulation of tumor necrosis factor production
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
liver regeneration
positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
regulation of rRNA processing
positive regulation of interleukin-6 secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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