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Proteintech
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Immunogen sequence: MAAYKLVLI RHGESAWNLE NRFSGWYDAD LSPAGHEEAK RGGQALRDAG YEFDICFTSV QKRAIRTLWT VLDAIDQMWL PVVRTWRLNE RHYGGLTGLN KAETAAKHGE AQVKIWRRSY DVPPPPMEPD HPFYSNISKD RRYADLTEDQ LPSCESLKDT IARALPFWNE EIVPQIKEGK RVLIAAHGNS LRGIVKHLEG LSEEAIMELN LPTGIPIVYE LDKNLKPIKP MQFLGDEETV RKAMEAVAAQ GKAKK
PGAM1 belongs to the phosphoglycerate mutase family. PGAM1 is an important component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM1 protein is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in PGAM1 cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BPG-dependent PGAM 1; epididymis secretory protein Li 35; PGAM-B; Phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase A, nonmuscle form; Phosphoglycerate mutase isozyme B; RP11-452K12.8
基因别名: 2310050F24Rik; CDABP0006; HEL-S-35; Pgam-1; PGAM-B; PGAM1; PGAMA; Pgmut
UniProt ID: (Human) P18669, (Rat) P25113, (Mouse) Q9DBJ1
Entrez Gene ID: (Human) 5223, (Rat) 24642, (Mouse) 18648