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Proteintech
eIF4G2/DAP5 Monoclonal Antibody (3C11A3), CoraLite® Plus 647
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eIF4G2/DAP5 Antibody (CL647-67428) in Flow
1X10^6 HeLa cells were intracellularly stained with 0.2 µg CoraLite® Plus 647 Anti-Human eIF4G2/DAP5 (CL647-67428, Clone:3C11A3) (red), or 0.2 µg APC-65124 ; APC Mouse IgG1 Isotype Control (APC-65124, Clone: MOPC-21) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
产品信息
CL647-67428
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
3C11A3
抗原
Recombinant protein
偶联物
激发/发射光谱
654/674 nm
形式
Liquid
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: EAVNGVREMR APKHFLPEML SKVIILSLDR SDEDKEKASS LISLLKQEGI ATSDNFMQAF LNVLDQCPKL EVDIPLVKSY LAQFAARAII SELVSISELA QPLESGTHFP LFLLCLQQLA KLQDREWLTE LFQQSKVNMQ KMLPEIDQNK DRMLEILEGK GLSFLFPLLK LEKELLKQIK LDPSPQTIYK WIKDNISPKL HVDKGFVNIL MTSFLQYISS EVNPPSDETD SSSAPSKEQL EQEKQLLLSF KPVMQKFLHD HVDLQVSALY ALQVHCYNSN FPKGMLLRFF VHFYDMEIIE EEAFLAWKED ITQEFPGKGK ALFQVNQWLT WLETAEEEES EEEAD
靶标信息
CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aging-associated protein 1; DAP-5; Death-associated protein 5; eIF-4-gamma 2; eIF-4G 2; eIF4G 2; EIF4G2; Eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4G-like 1; FLJ41344; Novel APOBEC-1 target 1; p97; Translation repressor NAT1
基因别名: AA589388; AAG1; DAP-5; DAP5; E130105L11Rik; EIF4G2; NAT1; Natm1; OK/SW-cl.75; P97
UniProt ID: (Human) P78344, (Mouse) Q62448
Entrez Gene ID: (Human) 1982, (Mouse) 13690, (Rat) 361628
