Proteintech

STIM1 Recombinant Rabbit Monoclonal Antibody (1B13), CoraLite® Plus 750

Name: STIM1 Recombinant Rabbit Monoclonal Antibody (1B13), CoraLite\u00AE Plus 750
Brand: Proteintech
SKU: CL750-81156

查看其他27个STIM1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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STIM1 Antibody (CL750-81156) in WB

Various lysates were subjected to SDS PAGE followed by western blot with CL750-81156 (STIM1 antibody) at dilution of 1:1,000 incubated at room temperature for 1.5 hours.

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Immunogen image

Immunogen Image STIM1 Recombinant Rabbit Monoclonal Antibody (1B13), CoraLite® Plus 750

产品信息

CL750-81156

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

CHO cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

1B13

抗原

STIM1 fusion protein Ag2140

查看免疫原

偶联物

CoraLite® Plus 750 CoraLite® Plus 750 CoraLite® Plus 750

激发/发射光谱

755/780 nm

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

内含物

0.05% ProClin 300

保存条件

-20°C, store in dark

运输条件

Wet ice

产品详细信息

Immunogen sequence: DVCVRLALWL LWGLLLHQGQ SLSHSHSEKA TGTSSGANSE ESTAAEFCRI DKPLCHSEDE KLSFEAVRNI HKLMDDDANG DVDVEESDEF LREDLNYHDP TVKHSTFHGE DKLISVEDLW KAWKSSEVYN WTVDEVVQWL ITYVELPQYE ETFRKLQLSG HAMPRLAVTN TTMTGTVLKM TDRSHRQKLQ LKALDTVLFG PPLLTRHNHL KDFMLVVSIV IGVGGCWFAY IQNRYSKEHM KKMMKDLEGL HRAEQSLHDL QERLHKAQEE HRTVEVEKVH LEKKLRDEIN LAKQEAQRLK ELREGTENER SRQKYAEEEL EQVREALRKA EKELESHSSW YAPEALQKW

靶标信息

STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.

仅用于科研。不用于诊断过程。未经明确授权不得转售。