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Invitrogen
CLEC4A Monoclonal Antibody (9E8), PE
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA574702
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
9E8
抗原
CD367 ectodomain fused with human Fc.
偶联物
PE
PE
PE
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
纯化类型
Size-exclusion chromatography
保存液
PBS, pH 7.4, with 0.2% BSA
内含物
15mM sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6; C-type lectin DDB27; C-type lectin DDB27 long form encoded by the sequence presented in GenBank Accession Number AF109146; C-type lectin superfamily member 6; dendritic cell immunoreceptor; lectin-like immunoreceptor
基因别名: CD367; CLECSF6; DCIR; DDB27; HDCGC13P; hDCIR; LLIR
UniProt ID: (Human) Q9UMR7
Entrez Gene ID: (Human) 50856
negative regulation of cytokine production
plasmacytoid dendritic cell antigen processing and presentation
cell adhesion
cell surface receptor signaling pathway
negative regulation of tumor necrosis factor production
CD8-positive, alpha-beta T cell activation
antigen processing and presentation of exogenous peptide antigen via MHC class I
antifungal innate immune response
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
