Invitrogen

CLEC4B Monoclonal Antibody (349214)

Name: CLEC4B Monoclonal Antibody (349214)
Brand: Invitrogen
SKU: MA5-24089

查看其他2个CLEC4B抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MA5-24089

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

0.25 µg per million cells

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

349214

抗原

Mouse myeloma cell line NS0-derived recombinant mouse DCAR/CLEC4B Gln42-Leu209

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2610616

产品详细信息

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

The CLEC4B gene encodes a member of the C-type lectin domain family and plays a significant role in immune system regulation, particularly involving the activation and modulation of neutrophils. CLEC4B is expressed in various immune cells, including neutrophils, where it contributes to controlling inflammatory responses and immune activation. It has been identified as a regulator of bystander activation of autoreactive and potentially pathogenic T cells, suggesting its involvement in limiting chronic inflammation. This gene participates in glycan recognition, which can induce the production of reactive oxygen species, thereby protecting tissues from oxidative stress and inflammatory damage. The role of CLEC4B extends to the regulation of neutrophil availability and function, exerting additive effects with other genes to modulate immune responses. CLEC4B's function in immune homeostasis presents potential therapeutic implications, particularly in autoimmune diseases and conditions involving excessive inflammation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。