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Invitrogen
CLEC9A Recombinant Human Monoclonal Antibody (9H7)
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产品信息
MA5-60831
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG4SP
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
9H7
抗原
Recombinant Human CLEC9A protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
C-type lectin domain family 9 member A (CLEC9A) is a gene located on chromosome 12p13.2, encoding a protein that belongs to the C-type lectin receptor family. CLEC9A is primarily expressed on dendritic cells and certain subsets of macrophages, playing a pivotal role in the immune system by recognizing and binding dead cell debris, including necrotic cells. This receptor facilitates the presentation of antigens derived from dead cells to T cells, thus contributing to the initiation of immune responses. CLEC9A is involved in cross-presentation, a process crucial for adaptive immunity, particularly in the context of viral infections and cancer. Its expression and activity are of particular interest for vaccine development and immunotherapy, given its ability to enhance antigen presentation and stimulate robust immune responses. Research into CLEC9A continues to explore its therapeutic potential for modulating immune activity in various diseases, including cancer and infectious diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-type lectin domain family 9 member A; C-type lectin domain family 9, member A; CD370; HEEE9341
基因别名: CD370; CLEC9A; DNGR-1; DNGR1; UNQ9341; UNQ9341/PRO34046
UniProt ID: (Human) Q6UXN8
Entrez Gene ID: (Human) 283420
