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Alomone Labs, LTD
CLIC1 Polyclonal Antibody
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CLIC1 Antibody (ACL-021-200UL) in ICC/IF
Expression of CLIC1 in human colorectal adenocarcinoma HT-29 cells - Immunocytochemical staining of fixed and permeabilized human colorectal adenocarcinoma HT-29 cells. A. Cells were stained with Anti-CLIC1 Antibody (#ACL-021), (1:200), followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Cell nuclei were visualized using Hoechst 33342 (blue). C. Merge of the two images.
产品信息
ACL-021-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)RGFTIPEAFRGVHR, corresponding to amino acid residues 195-208 of human CLIC1, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chloride channel ABP; Chloride intracellular channel protein 1; chloride intracellular channel protein 1 {ECO:0000250|UniProtKB:O00299, ECO:0000312|EMBL:CAE83985.1}; clic1 {ECO:0000312|EMBL:CAE83985.1, ECO:0000312|RGD:1303043}; DADB-110M10.1; FLJ94671; Glutaredoxin-like oxidoreductase CLIC1; Glutathione-dependent dehydroascorbate reductase CLIC1; hRNCC; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; Regulatory nuclear chloride ion channel protein; RNCC protein
基因别名: Clcp; CLIC1; G6; NCC27
UniProt ID: (Human) O00299, (Mouse) Q9Z1Q5, (Rat) Q6MG61
Entrez Gene ID: (Human) 1192, (Mouse) 114584, (Rat) 406864
glutathione metabolic process
chloride transport
signal transduction
regulation of ion transmembrane transport
positive regulation of osteoblast differentiation
regulation of cell cycle
regulation of mitochondrial membrane potential
platelet aggregation
chloride transmembrane transport
transport
ion transport
regulation of anion transport
