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Invitrogen
CLIC3 Polyclonal Antibody
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CLIC3 Antibody (PA5-90398) in WB
Western blot analysis of CLIC3 in extracts of various cell lines. Samples were incubated with CLIC3 Polyclonal antibody (Product # PA5-90398) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-90398
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 87-236 of human CLIC3 (NP_0046602)
偶联物
形式
Liquid
浓度
1.43 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GPPDFPSLAP RYRESNTAGN DVFHKFSAFI KNPVPAQDEA LYQQLLRALA RLDSYLRAPL EHELAGEPQL RESRRRFLDG DRLTLADCSL LPKLHIVDTV CAHFRQAPIP AELRGVRRYL DSAMQEKEFK YTCPHSAEIL AAYRPAVHPR; Positive Samples: HeLa, Mouse lung, Rat lung; Cellular Location: Cytoplasm, Membrane, Nucleus, Single-pass membrane protein
靶标信息
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chloride intracellular channel protein 3; Glutaredoxin-like oxidoreductase CLIC3; RP11-229P13.3
基因别名: 2300003G24Rik; CLIC3
UniProt ID: (Human) O95833, (Mouse) Q9D7P7
Entrez Gene ID: (Human) 9022, (Mouse) 69454, (Rat) 296566
