Invitrogen

CLOCK Polyclonal Antibody

查看其他14个CLOCK抗体

问题与答案

问题与答案

问题与答案

抗体检测数据 (1)

CLOCK Antibody in Western Blot (WB)

CLOCK Antibody in Western Blot (WB)

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CLOCK Antibody (PA5-143080) in WB

Western Blot analysis of CLOCK in Mouse (A) and Rat (B) Skeletal Muscle lysate (35 µg protein in RIPA buffer) using CLOCK Polyclonal Antibody (Product # PA5-143080) at 0.03 µg/mL incubated for 1 hour. Detected by chemiluminescence.

CLOCK Antibody in Western Blot (WB)

Product Image Gallery

CLOCK Antibody in Western Blot (WB) — Western Blot analysis of CLOCK in Mouse (A) and Rat (B) Skeletal Muscle lysate (35 µg protein in RIPA buffer) using CLOCK Polyclonal Antibody (Product # PA5-143080) at 0.03 µg/mL incubated for 1 hour. Detected by chemiluminescence.

Immunogen image

CLOCK Polyclonal Antibody

Immunogen Image CLOCK Polyclonal Antibody

产品信息

PA5-143080

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.03-0.1 µg/mL

-

产品规格

种属反应

Mouse, Rat

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide with sequence C-DTSTPPRQHLPAHEK.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

靶标信息

This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: circadian locomoter output cycles kaput; Circadian locomoter output cycles protein kaput; mCLOCK; rCLOCK

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基因别名: 5330400M04Rik; Clock; KAT13D

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UniProt ID: (Mouse) O08785, (Rat) Q9WVS9

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Entrez Gene ID: (Mouse) 12753, (Rat) 60447

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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding histone acetyltransferase activity signal transducer activity protein binding transcription factor binding transferase activity transferase activity, transferring acyl groups chromatin DNA binding sequence-specific DNA binding protein dimerization activity E-box binding

DNA damage checkpoint transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter cellular response to DNA damage stimulus signal transduction spermatogenesis circadian rhythm histone acetylation circadian regulation of gene expression regulation of hair cycle proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter rhythmic process positive regulation of inflammatory response regulation of insulin secretion positive regulation of NF-kappaB transcription factor activity response to redox state cellular response to ionizing radiation regulation of type B pancreatic cell development negative regulation of glucocorticoid receptor signaling pathway entrainment of circadian clock