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Invitrogen
CMYA5 Polyclonal Antibody
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产品信息
PA5-140296
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human CMYA5. Recombinant protein control fragment (Product #RP-109651).
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: FISEVSREDY GKKEISGDSE EMNINSVVTS ADGENLEIQS YSLIGEKLVM EEAKTIVPPH VTDSKRVQKP AIAPPSK
Highest antigen sequence indentity to the following orthologs: Rat - 48%, Mouse - 40%.
靶标信息
SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2310076E16Rik; Cardiomyopathy-associated protein 5; Dystrobrevin-binding protein 2; Genethonin-3; Myospryn; SPRY domain-containing protein 2; tripartite motif-containing 76; Tripartite motif-containing protein 76
基因别名: C5orf10; CMYA5; DTNBP2; SPRYD2; TRIM76
UniProt ID: (Human) Q8N3K9
Entrez Gene ID: (Human) 202333
