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Invitrogen
COBL Polyclonal Antibody
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FIGURE: 1 / 6
COBL Antibody (PA5-53897) in IHC
Immunohistochemical staining of COBL in human cerebral cortex, colon, heart muscle and smooth muscle using COBL Polyclonal Antibody (Product # PA5-53897) (A) shows similar protein distribution across tissues to an independent COBL Polyclonal Antibody (B).
Product Details
PA5-53897
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human COBL. Recombinant protein control fragment (Product #RP-92659).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KSAHHEGRNP LGEGRNQPPT MGMGHVRVPA AHTTEVTFLK PQRRTSSQYV ASAIAKRIGA PKVHADVVRP HGYAEKGYAG KAPVLAAPPV TVKDDRTSSP HSETQGWKDG AQWPCVTPPN NHGEDLAVGA
Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 46%.
Target Information
This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. Alternatively spliced transcript variants of this gene have been found; however, their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cordon-bleu homolog; Protein cordon-bleu
Gene Aliases: COBL; KIAA0633
UniProt ID: (Human) O75128
Entrez Gene ID: (Human) 23242
embryonic axis specification
somite specification
neural tube closure
liver development
actin filament polymerization
notochord development
floor plate development
digestive tract development
collateral sprouting in absence of injury
actin filament network formation
positive regulation of dendrite development
positive regulation of ruffle assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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