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Invitrogen
COL11A2 Polyclonal Antibody
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COL11A2 Antibody (PA5-116517) in WB
Western blot analysis of COL11A2 in extracts of various cell lines. Samples were incubated with COL11A2 Polyclonal antibody (Product # PA5-116517) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-116517
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 210-380 of human COL11A2 (NP_5424112)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.49 mg/mL
规格
49 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: A375, HepG2, K-562
Immunogen sequence: IVPGVQAAYE SCEQKELECE GGQRERPQNQ QPHRAQRSPQ QQPSRLHRPQ NQEPQSQPTE SLYYDYEPPY YDVMTTGTTP DYQDPTPGEE EEILESSLLP PLEEEQTDLQ VPPTADRFQA EEYGEGGTDP PEGPYDYTYG YGDDYREETE LGPALSAETA HSGAAAHGPR G
靶标信息
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Collagen alpha-2(XI) chain; DAQB-79P13.8; HGNC:2187
基因别名: COL11A2
Entrez Gene ID: (Human) 1302
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