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Invitrogen
COL15A1 Polyclonal Antibody
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COL15A1 Antibody (PA5-115179) in ICC/IF
Immunocytochemistry analysis of COL15A1 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115179) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
产品信息
PA5-115179
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human COL15A1(Accession P39059), corresponding to amino acid residues A272-I322.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Endostatin.
靶标信息
This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: COFA1; Collagen alpha-1(XV) chain; collagen type XV proteoglycan; collagen XV, alpha-1 polypeptide; collagen, type XV, alpha 1; endostatin-XV; procollagen type XV; procollagen, type XV; restin; type XV collagen
基因别名: COL15A1
UniProt ID: (Human) P39059, (Mouse) O35206
Entrez Gene ID: (Human) 1306, (Mouse) 12819, (Rat) 298069
