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Invitrogen
COL6A1 Polyclonal Antibody
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COL6A1 Antibody (PA5-121228) in WB
Western blot analysis of COL6A1 in extracts of various cell lines. Samples were incubated with COL6A1 Polyclonal antibody (Product # PA5-121228) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-121228
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 19-250 of human Collagen VI/Collagen VI/COL6A1 (NP_0018392)
偶联物
形式
Liquid
浓度
1.37 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: SKOV3, HepG2, HT-1080, Mouse heart, Mouse lung, Mouse pancreas. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence: AQDEPETPRA VAFQDCPVDL FFVLDTSESV ALRLKPYGAL VDKVKSFTKR FIDNLRDRYY RCDRNLVWNA GALHYSDEVE IIQGLTRMPG GRDALKSSVD AVKYFGKGTY TDCAIKKGLE QLLVGGSHLK ENKYLIVVTD GHPLEGYKEP CGGLEDAVNE AKHLGVKVFS VAITPDHLEP RLSIIATDHT YRRNFTAADW GQSRDAEEAI SQTIDTIVDM IKNNVEQVCC SF
靶标信息
The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (typesI, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 1 (VI) chain (61 AA); Collagen alpha-1(VI) chain; collagen VI, alpha-1 polypeptide; collagen, type VI, alpha 1; procollagen, type VI, alpha 1
基因别名: AI747156; BTHLM1; Col6a-1; COL6A1; OPLL; UCHMD1
UniProt ID: (Human) P12109, (Mouse) Q04857
Entrez Gene ID: (Human) 1291, (Mouse) 12833
