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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Samples: SW620, U-251MG, HepG2, MCF7, Mouse skeletal muscle; Cellular Location: extracellular matrix, extracellular space
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); COMP; MGC131819; MGC149768; multiple epiphyseal dysplasia; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); Thrombospondin-5; Thrombospondin5; TSP 5; TSP5; unnamed protein product
基因别名: COMP; CTS2; EDM1; EPD1; MED; PSACH; THBS5; TSP-5; TSP5
UniProt ID: (Mouse) Q9R0G6, (Rat) P35444
Entrez Gene ID: (Human) 1311, (Mouse) 12845, (Rat) 25304