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Abnova
CORO1C Monoclonal Antibody (1F7)
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产品信息
H00023603-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1F7
抗原
CORO1C (NP_055140, 375 a.a. approximately 473 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: EEWFEGKNAD PILISLKHGY IPGKNRDLKV VKKNILDSKP TANKKCDLIS IPKKTTDTAS VQNEAKLDEI LKEIKSIKDT ICNQDERISK LEQQMAKIA
靶标信息
Coronin 3 is associated with the aggression and metastasis of hepatocellular carcinoma. Coronins are a family of highly evolutionary conserved proteins reportedly involved in the regulation of actin cytoskeletal dynamics, although only coronin 3 has been shown to be related to cancer cell migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: coronin, actin binding protein, 1C; coronin, actin-binding protein, 1C; Coronin-1C; Coronin-3; hCRNN4
基因别名: CORO1C; CRN2; CRNN4; HCRNN4
UniProt ID: (Human) Q9ULV4
Entrez Gene ID: (Human) 23603
neural crest cell migration
regulation of protein phosphorylation
negative regulation of protein phosphorylation
phagocytosis
signal transduction
regulation of epithelial cell migration
negative regulation of epithelial cell migration
regulation of fibroblast migration
actin cytoskeleton organization
negative regulation of protein kinase activity by regulation of protein phosphorylation
establishment of protein localization
regulation of focal adhesion assembly
negative regulation of focal adhesion assembly
activation of GTPase activity
regulation of substrate adhesion-dependent cell spreading
negative regulation of substrate adhesion-dependent cell spreading
regulation of ruffle assembly
positive regulation of lamellipodium morphogenesis
