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Invitrogen
COX3 Polyclonal Antibody
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COX3 Antibody (PA5-97297) in WB
Western blot analysis of COX3 in extracts of various cell lines. Samples were incubated with COX3 Polyclonal antibody (Product # PA5-97297) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-97297
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of mouse MT-CO3 (NP_9043341)
偶联物
形式
Liquid
浓度
0.36 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MTHQTHAYHM VNPSPWPLTG AFSALLLTSG LVMWFHYNSI TLLTLGLLTN ILTMYQWWRD VIREGTYQGH HTPIVQKGLR YGMILFIVSE VFFFAGFFWA; Positive Samples: Mouse liver, Rat liver; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein
靶标信息
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Co3; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3
基因别名: COIII; Mt-co3; Mtco3
UniProt ID: (Mouse) P00416
Entrez Gene ID: (Mouse) 17710
