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Recommended positive controls: Raji.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COX VIa-M; COXVIAH; Cytochrome c oxidase polypeptide VIa-heart; Cytochrome c oxidase subunit 6A2, mitochondrial; cytochrome c oxidase subunit VIa polypeptide 2; Cytochrome c oxidase subunit VIA-muscle; subunit VIaH (heart-type)
基因别名: COX6A; COX6A2; COX6AH; COXVIAH; VIaH
UniProt ID: (Human) Q02221, (Mouse) P43023
Entrez Gene ID: (Human) 1339, (Mouse) 12862