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Invitrogen
COX8C Polyclonal Antibody
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产品信息
PA5-103395
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human COX8C(Accession Q7Z4L0), corresponding to amino acid residues R5-F55.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Cytochrome c Oxidase 8C.
靶标信息
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport. This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COX VIII-3; COX8-3; cytochrome c oxidase polypeptide 8; Cytochrome c oxidase polypeptide 8 isoform 3; cytochrome c oxidase polypeptide VIII; Cytochrome c oxidase polypeptide VIII isoform 3; Cytochrome c oxidase subunit 8-3; Cytochrome c oxidase subunit 8C, mitochondrial; cytochrome c oxidase subunit VIII; Cytochrome c oxidase subunit VIIIC
基因别名: 1700007F21Rik; COX8-3; COX8C; COXVIII-3
UniProt ID: (Human) Q7Z4L0, (Mouse) A6H666
Entrez Gene ID: (Human) 341947, (Mouse) 75483
