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Invitrogen
CRB1 Polyclonal Antibody
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CRB1 Antibody (PA5-143856) in IHC (P)
Immunohistochemistry analysis of CRB1 in paraffin-embedded section of human testis cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH 6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. Samples were incubated with CRB1 Polyclonal antibody (Product # PA5-143856) using a dilution of 1 μg/mL overnight at 4°C. Biotinylated goat anti-ra... View More
产品信息
PA5-143856
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human CRB1 (FRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQ).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human HEK293 whole cell, human U-87MG whole cell. IHC: mouse testis tissue, human testis cancer tissue, rat testis tissue, human glioma tissue. Flow: U87 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: crumbs family member 1, photoreceptor morphogenesis associated; Crumbs homolog 1; Protein crumbs homolog 1
基因别名: 7530426H14Rik; A930008G09Rik; CRB1; LCA8; RP12
UniProt ID: (Human) P82279, (Mouse) Q8VHS2
Entrez Gene ID: (Human) 23418, (Rat) 304825, (Mouse) 170788
