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Immunogen sequence: MRHSLTKLLA ASGSNSPTRS ESPEPAATCS LPSDLTRAAA GEEETAAAGS PGRKQQFGDE GELEAGRGSR GGVAVRAPSP EEMEEEAIAS LPGEETEDMD FLSGLELADL LDPRQPDWHL DPGLSSPGPL SSSGGGSDSG GLWRGDDDDE AAAAEMQRFS DLLQRLLNGI GGCSSSSDSG SAEKRRRKSP GGGGGGGSGN DNNQAATKSP RKAAAAAARL NRLKKKEYVM GLESRVRGLA AENQELRAEN RELGKRVQAL QEESRYLRAV LANETGLARL LSRLSGVGLR LTTSLFRDSP AGDHDYALPV GKQKQDLLEE DDSAGGVCLH VDKDKVSVEF CSACARKASS SLKM; Positive Samples: LO2, 293T, HeLa, U-87MG, K-562, Mouse brain, Mouse heart, Rat brain; Cellular Location: Nucleus
Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CREB/ATF bZIP transcription factor; HCF-binding transcription factor Zhangfei; Host cell factor-binding transcription factor Zhangfei; SHP-interacting leucine zipper protein; Tyrosine kinase-associated leucine zipper protein LAZip; tyrosine kinase-associated leucine zipper protein LAZipII; Zhangfei
基因别名: 1110034C16Rik; 6330417B10Rik; CREBZF; LAZip; LAZipII; RGD1565584; SMILE; ZF
UniProt ID: (Human) Q9NS37, (Mouse) Q91ZR3
Entrez Gene ID: (Human) 58487, (Mouse) 233490, (Rat) 293112