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Invitrogen
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Peptide Sequence: VTPGAGRFVP RKTFPDFVYK RIKARNRLAE IHGVPRGLYD GPVHEVMVPA KPGSGAPARA SCPGKISVPP VRNLHQSGFS LSGSQADDHI ARRTAQKIM
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Collapsin response mediator protein 3; CRMP-3; dihydropyrimidinase-like 4; Dihydropyrimidinase-related protein 4; DRP-4; ULIP-4; UNC33-like phosphoprotein 4
基因别名: CRMP3; DPYSL4; DRP-4; ULIP4
UniProt ID: (Human) O14531
Entrez Gene ID: (Human) 10570