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Invitrogen
CTDSPL Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-61713
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AIITQVTNPK EDEGRLPGAG EKASQCNVSL KKQRSRSILS SFFCCFRDYN VEAPPPSSPS VLPPLVEENG GLQKGDQ
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 41%.
靶标信息
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like; CTDSP-like; MGC71888; NIF-like protein; NLI-interacting factor 1; nuclear LIM interactor-interacting factor 1; RB protein serine phosphatase from chromosome 3; SCP-3; SCP3; SCP3 COR1; small C-terminal domain phosphatase 3; small CTD phosphatase 3
基因别名: C3orf8; HYA22; PSR1; RBSP3; SCP3
UniProt ID: (Human) O15194
Entrez Gene ID: (Human) 10217
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