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Invitrogen
CTGF Monoclonal Antibody (CL5339)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-31420
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CL5339
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LPSPDCPFPR RVKLPGKCCE EWVCDEPKDQ TVVGPALAAY RLEDTFGPDP TMIRANCLVQ TTEWSACSKT CGMG
Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 96%.
靶标信息
Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 2-Nov; cellular communication network factor 1; connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); connective tissue growth-related protein; CTGF; CTGRP; fibroblast inducible secreated protein; fibroblast inducible secreted protein; H-CTGF; hypertrophic chondrocyte-specific gene product 24; hypertrophic chondrocyte-specific protein 24; IGF-binding protein 8; insulin-like growth factor-binding protein 8; MGC102839; unnamed protein product
基因别名: CTGF; CTGRP; fisp-12; Fisp12; HCS24; IBP-8; IGFBP8; KMD; NOV2; SEMDLSL
UniProt ID: (Human) P29279, (Mouse) P29268, (Rat) Q9R1E9
Entrez Gene ID: (Human) 1490, (Mouse) 14219, (Rat) 64032
osteoblast differentiation
cell adhesion
signal transduction
epidermis development
response to wounding
positive regulation of cell differentiation
positive regulation of JNK cascade
regulation of developmental process
positive regulation of stress fiber assembly
positive regulation of ERK1 and ERK2 cascade
cartilage condensation
ossification
angiogenesis
tissue homeostasis
positive regulation of protein phosphorylation
microtubule depolymerization
cell-matrix adhesion
integrin-mediated signaling pathway
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of gene expression
negative regulation of gene expression
cell migration
cell differentiation
lung development
regulation of chondrocyte differentiation
positive regulation of collagen biosynthetic process
intracellular signal transduction
chondrocyte proliferation
positive regulation of cell activation
regulation of multicellular organismal process
positive regulation of cardiac muscle contraction
connective tissue development
extracellular matrix constituent secretion
positive regulation of G0 to G1 transition
reactive oxygen species metabolic process
calcium ion transmembrane import into cytosol
positive regulation of apoptotic signaling pathway
response to gamma radiation
response to estradiol
response to anoxia
cellular response to interleukin-13
response to amino acid
response to peptide hormone
response to mineralocorticoid
response to fatty acid
cellular response to glucose stimulus
cellular response to fatty acid
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