Search
Bethyl Laboratories
CTHRC1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 1
CTHRC1 Antibody (A305-863A-T) in WB
Detection of human and mouse CTHRC1 by western blot. Samples: Whole cell lysate (50 µg) from UACC-62, Malme-3M, SR, and NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified Rabbit anti-CTHRC1 antibody A305-863A-M (lot A305-863A-M-1) used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 10 seconds.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A305-863A-T
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A region between residue 193 and 243 of human Collagen triple helix repeat-containing protein 1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Predicted reactivity by homology: Rat.
靶标信息
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: matrix protein; unnamed protein product
基因别名: 1110014B07Rik
UniProt ID: (Human) Q96CG8, (Mouse) Q9D1D6
Entrez Gene ID: (Human) 115908, (Mouse) 68588
cell migration
cyclooxygenase pathway
positive regulation of osteoblast proliferation
ossification involved in bone remodeling
positive regulation of osteoblast differentiation
Wnt signaling pathway, planar cell polarity pathway
inner ear receptor stereocilium organization
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
establishment of planar polarity involved in neural tube closure
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
