Invitrogen

CTRL Polyclonal Antibody

Name: CTRL Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-56958

高级验证

查看其他4个CTRL抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (8)
高级验证 (1)

CTRL Antibody in Immunohistochemistry (IHC)

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CTRL Antibody (PA5-56958) in IHC

Immunohistochemical staining of CTRL in human cerebral cortex, liver, lymph node and pancreas using CTRL Polyclonal Antibody (Product # PA5-56958) (A) shows similar protein distribution across tissues to an independent CTRL Polyclonal Antibody (B).

Product Image Gallery

CTRL Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of CTRL demonstrates antibody specificity. Immunohistochemical analysis of CTRL using anti-CTRL Polyclonal Antibody (Product # PA5-56958), shows significant staining of CTRL in human pancreas and shows minimal or weak staining in human colon tissues. The relative expression levels of CTRL within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image CTRL Polyclonal Antibody

产品信息

PA5-56958

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:1,000-1:2,500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human CTRL. Recombinant protein control fragment (Product #RP-95844).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2640235

产品详细信息

Immunogen sequence: VTAAHCNVSP GRHFVVLGEY DRSSNAEPLQ VLSVSRAITH PSWNSTTMNN DVTLLK

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.

靶标信息

The CTRL gene encodes chymotrypsin-like protein, a serine protease involved in the digestion of proteins by cleaving peptide bonds. It belongs to the chymotrypsin family of enzymes that are predominantly expressed in the pancreas and play crucial roles in the breakdown of dietary proteins in the small intestine. CTRL functions by hydrolyzing specific peptide bonds, contributing to efficient protein digestion and nutrient absorption. This enzyme's activity is tightly regulated to prevent premature activation within the pancreas, which could lead to pancreatitis or other digestive disorders. The study of the CTRL gene is significant in understanding the mechanisms of digestive health and in diagnosing pancreatic disorders. Furthermore, CTRL's enzyme activity and its role in proteolytic pathways make it an important target for research in digestive enzyme supplementation therapies and treatment strategies for conditions involving impaired protein digestion.

仅用于科研。不用于诊断过程。未经明确授权不得转售。