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Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: HHGVTKCNIT CSKMTSKIPV ALLIHYQQNQ ASCGKRAIIL ETRQHRLFCA DPKEQWVKDA MQHLDRQAAA LTRNGGTFEK QIGEVKPRTT PAAGGMDESV VLEPEATGES
Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-X3-C motif chemokine 1; chemokine (C-X3-C motif) ligand 1; CX3C membrane-anchored chemokine; Fractalkine; Neurotactin; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); small inducible cytokine subfamily D (Cys-X3-Cys), member-1; Small-inducible cytokine D1
基因别名: A-152E5.2; ABCD-3; C3Xkine; CX3CL1; CXC3; CXC3C; FKN; fractalkine; neurotactin; NTN; NTT; SCYD1
UniProt ID: (Human) P78423
Entrez Gene ID: (Human) 6376