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Invitrogen
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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human I-TAC/CXCL11.
Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Beta-R1; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 11; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; H174; I-TAC; Interferon gamma-inducible protein 9; Interferon-inducible T-cell alpha chemoattractant; IP-9; MGC102770; Small-inducible cytokine B11
基因别名: CXCL11; ITAC; SCYB11; SCYB9B
Entrez Gene ID: (Human) 6373