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Invitrogen
CXCL12 Monoclonal Antibody (79018), FITC
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CXCL12 Antibody (MA5-23547) in Flow
Flow cytometry of CXCL12 in MG‚63 human osteosarcoma cell line. Samples were incubated in CXCL12 monoclonal antibody (Product # MA5-23547) or isotype control. To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer and permeabilized with Flow Cytometry Permeabilization/Wash Buffer.
产品信息
MA5-23547
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
C. elegans,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
79018
抗原
E. coli-derived recombinant human CXCL12/SDF-1 alpha Lys22-Lys89
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
纯化类型
Protein A/G
保存液
Buffered saline solution with ≤ 0.5% BSA
内含物
0.09% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
生物信息学
蛋白别名: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; AI174028; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 12; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; CXC; CXC motif chemokine; CXCL; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; Pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SDF-1; SDF-1a; SDF-1b; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; Thymic lymphoma cell-stimulating factor; TLSF; TLSF-a; TLSF-b; Tlsfa; Tlsfb; TPAR1
基因别名: CXCL12; IRH; PBSF; SCYB12; SDF1; SDF1A; SDF1B; TLSF; TPAR1
UniProt ID: (Human) P48061, (Mouse) Q4FJL5
Entrez Gene ID: (Human) 6387, (Mouse) 20315
patterning of blood vessels
ameboidal-type cell migration
neuron migration
positive regulation of endothelial cell proliferation
chemotaxis
immune response
germ cell development
brain development
motor neuron axon guidance
positive regulation of cell proliferation
adult locomotory behavior
germ cell migration
telencephalon cell migration
regulation of cell migration
positive regulation of cell migration
organ regeneration
positive regulation of dopamine secretion
T cell proliferation
positive regulation of neuron differentiation
positive regulation of cell adhesion
positive regulation of axon extension involved in axon guidance
induction of positive chemotaxis
regulation of calcium ion transport
cell chemotaxis
chemokine-mediated signaling pathway
positive regulation of monocyte chemotaxis
positive regulation of myoblast fusion
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of leukocyte tethering or rolling
negative regulation of leukocyte apoptotic process
positive regulation of T cell migration
response to hypoxia
cellular calcium ion homeostasis
cell adhesion
signal transduction
G-protein coupled receptor signaling pathway
axon guidance
blood circulation
regulation of actin polymerization or depolymerization
response to radiation
response to heat
response to mechanical stimulus
response to virus
response to peptide hormone
positive chemotaxis
positive regulation of calcium ion import
