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Invitrogen
CXCL17 Monoclonal Antibody (510614)
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产品信息
MA5-24222
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
C. elegans
宿主/亚型
Rat
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
510614
抗原
E. coli-derived recombinant mouse CXCL17/VCC-1 Ser31-Leu119
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects recombinant mouse (rm) CXCL17/VCC-1 in direct ELISAs and Western blots. In direct ELISAs, 50% cross-reactivity with recombinant human CXCL17 is observed/VCC-1.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 13.6 kDa protein; 13.6-kDa protein; 6-Cys CXCL17; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 17; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; VEGF co-regulated chemokine 1; VEGF coregulated chemokine 1
基因别名: Cxcl17; VCC-1; Vcc1
UniProt ID: (Mouse) Q5UW37
Entrez Gene ID: (Mouse) 232983
