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Invitrogen
CXCR7 Monoclonal Antibody (734110)
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产品信息
MA5-61773
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
734110
抗原
E. coli-derived recombinant mouse CXCR7/RDC-1 extracellular N-terminus and loops, Met1-Leu47, Ser103-Lys118, Lys184-Glu213, Leu274-Ala296
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
IgM
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Atypical chemokine receptor 3; C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 7; CC motif chemokine; CCmotif chemokine; chemokine; chemokine (C-X-C motif) receptor 7; Chemokine orphan receptor 1; CXC; CXC motif chemokine; CXC-R7; G-protein coupled receptor RDC1 homolog; RDC-1
基因别名: Ackr3; AW541270; Cmkor1; CXC-R7; CXCR-7; Cxcr7; RDC-1; Rdc1
UniProt ID: (Mouse) P56485
Entrez Gene ID: (Mouse) 12778
angiogenesis
vasculogenesis
positive regulation of defense response to virus by host
chemotaxis
cell adhesion
signal transduction
G-protein coupled receptor signaling pathway
multicellular organism development
receptor internalization
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
